Dr. Anna-Katharina Dehof
Employment:
Researcher
Personal:
This is the personal site of Anna-Katharina Dehof.
Education:
| since 04/2012 | Postdoctoral researcher at chair of Prof. Lenhof, Center for Bioinformatics |
| 03/2012 | PhD-thesis at Graduate School of Saarland University, chair of Prof. Lenhof, Center for Bioinformatics |
| 04/2007 | Master's Degree, Saarland University |
| 10/2005 | Bachelor's Degree, Saarland University |
| 2004 | Summer placement at the Bioinformatics Research Center at Glasgow University |
| 2002-2007 | Studies in Computational Biology at Saarland University |
| 1999-2002 | Job training as Mathematisch-Technische Assistentin/Informatik (IHK) at AXA Tech |
Research:
My current research interests are in the fields of structure based bioinformatics:
- NMR-based structure analysis and docking algorithms (Drug Design and Machine Learning)
- Real time ray tracing techniques in Molecular Visualization for the molecular viewing and editing tool BALLView
- Optimization techniques, e.g., for bond order assignment (Cheminformatics)
- Computational Proteomics
- Image Processing
- The BALL project
- Development of web interfaces for bioinformatic services (ballaxy)
- Bioinformatics education, e.g. MSWissenschaft
Teaching:
Lectures, seminars, courses
- TA Bioinformatics 1 (WS 07/08, WS 08/09, WS 09/10, WS 10/11, WS 11/12)
- TA Bioinformatics 2 (SS06, SS07, SS09, SS11, SS12)
- TA "Fighting Cancer in Bioinformatics"(SS 08)
- Proseminar "Bioinformatic Approaches for Cancer Research" (repeatedly 2007-2012)
- Proseminar "Efficient Algorithms for RNA molecules" (repeatedly 2007-2012)
- Seminar "Modelling and Analyzing Biological Networks" (repeatedly 2007-2012)
- Seminar "Selected Topics in Molecular Docking" (repeatedly 2007-2012)
- Seminar "Computation in Systems Biology" (WS 07/08)
- Girl's Day / Girl's Camp (SS07, SS 08, SS09, WS 09/10)
Diploma, Bachelor's and Master's thesis
- "Erweiterung und Evaluierung von BALLView und des Präsentationsframeworks PresentaBALL für den Einsatz im Chemieunterricht an weiterführenden Schulen" (Markus Konietzko, SS12)
- "Design and implementation of the functionality to align sequences and structures into the Biochemical Algorithms Library" (Nikola Koch, SS12)
- "Implementation of a Graph Coloring Algorithm for InChi Computation" (Alexander Zapp, SS12)
- "pKa-dependent Bond Order Assignment of Organic Molecules" (Adrian Fritz, WS11/12)
- "Statistical Analysis of Bond Orders in Ligand Molecules" (Alexander Gress, SS12)
- "A hybrid model for NMR chemical shift prediction" (Simon Loew, WS10/11)
- "Structural Stability and Immunogenicity of Peptides" (Eva Kranz, WS09/10)
- "TNF alpha antibody design" (Miriam Mangels , WS09/10)
My Publications
2013
[DLL+13]
Dehof, A.K., Loew, S., Lenhof, H.-P., & Hildebrandt, A. (2013).
NightShift: NMR Shift Inference by General Hybrid Model Training - a Framework for NMR Chemical Shift Prediction.
BMC Bioinformatics. 2013 Mar 16;14(1):98. [Epub ahead of print]
2012
[NSM+12]
Nickels, S, Sminia, H, Mueller, S, Kools, B, A.K. Dehof, H.-P. Lenhof, and A. Hildebrandt: (2012) ProteinScanAR - An augmented reality web application for high school education in biomolecular life sciences. Proceedings of the 6th International Symposium on Information Visualization in Biomedical Informatics (IVBI 2012).
2011
[DLH11] Dehof, A.K., Lenhof, H.-P. & Hildebrandt, A. (2011). Predicting Protein NMR Chemical Shifts in the Presence of Ligands and Ions using Force Field-based Features. Proceedings of the German Conference on Bioinformatics (GCB 2011).
[DRB+11] Dehof, A.K., Rurainski, A., Bui, Q.B.A., Böcker, S., Lenhof, H.-P. & Hildebrandt, A. (2011). Automated Bond Order Assignment as an Optimization Problem. Bioinformatics, 2011 January 17 [E pub ahead of print].
2010
[HDR+10] Hildebrandt, A., Dehof, A.K., Rurainski, A., Bertsch, A., Schumann, M., Toussaint, N.C., Moll, A., Stöckel, D., Nickels, S., Müller, S.C., Lenhof, H.-P. & Kohlbacher, O. (2010). BALL - Biochemical Algorithms Library 1.3. BMC Bioinformatics, 2010, 11:531.
[SER+10]
K.K. Singh, S. Erkelenz, S. Rattay, A.K. Dehof, A. Hildebrandt, K. Schulze-Osthoff, H. Schaal, and C. Schwerk: (2010) Human SAP18 mediates assembly of a splicing regulatory multiprotein complex via its ubiquitin-like fold. RNA, 2010, 16(12), 2442-2454.
[MDGL+10] L. Marsalek, A.K. Dehof, I. Georgiev, H.-P. Lenhof, P. Slusallek and A. Hildebrandt: (2010) Real-time Ray Tracing of Complex Molecular Scenes. Proceedings of the IVbm 10 - Information Visualization in Biomedical Informatics
[PGDN+10] M. Phillips, I. Georgiev, A.K. Dehof, L. Marsalek, H.-P. Lenhof, A. Hildebrandt, and P. Slusallek: (2010) Measuring Properties of Molecular Surfaces Using Ray Casting. HiCOMB 2010, Proceedings of 9th International Workshop on High Performance Computational Biology
2009
[DGMS+09]
A. K. Dehof, I. Georgiev, L. Marsalek, D. Stöckel, S. Nickels, H.-P. Lenhof, P. Slusallek and A. Hildebrandt (2009): Visual Computing in Computer Aided Drug Design. Visual Computing Research Conference, Saarbrücken, Germany, 8-10 December 2009
[DRLH09] A. K. Dehof, A. Rurainski, H.-P. Lenhof and A. Hildebrandt: (2009) Automated Bond Order Assignment as an Optimization Problem. Proceedings of GCB 2009 (German Conference on Bioinformatics, Halle (Saale), Germany, 28-30 Sep 2009), Lecture Notes in Informatics, 2009
[BRFD+05]
K.H. Brämswig, A.B. Riemer, E. Förster-Waldl, A. Dehof, D. Neumann, H.N. Lode, C. Zielinski, O. Scheiner, H. Pehamberger, E. Jensen-Jarolim (2005): Generation of Peptide mimics of Melanoma Antigen GD2. Proceedings of the 35th Annual European Society for Dermatological Research (ESDR) Meeting, Journal of Investigative Dermatology 125(S1:A35)
[FRDN+05]
E. Förster-Waldl, A.B. Riemer, A.K. Dehof, D. Neumann, K.H. Brämswig, G. Boltz-Nitulescu, H. Pehamberger, C. Zielinski, O. Scheiner, A. Plloak, H.N. Lode, and E. Jensen-Jarolim: (2004) Isolation and structural analysis of peptide mimotopes for the disialoganglioside GD2, a neuroblastoma tumor antigen Molecular Immunology
