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Prof. Dr. Hans-Peter Lenhof


This is the personal page of Hans-Peter Lenhof

My Publications


[SMK+13] Stöckel, D., Müller, O., Kehl, T., Gerasch, A., Backes, C., Rurainski, A., Keller, A., Kaufmann, M., and Lenhof, H.-P.: NetworkTrail - A web service for identifying and visualizing deregulated subnetworks. Bioinformatics 29 (13):1702-03, 2013.
[LBH+13] Li, D., Beisswenger, C., Herr, C., Hellberg, J., Han, G., Zakharkina, T., Voss, M., Wiewrodt, R., Bohle, R.M., Menger, M.D., Schmid, R.M., Stöckel, D., Lenhof, H.-P., and Bals, R.: Myeloid cell RelA/p65 promotes lung cancer proliferation through Wnt/β-catenin signaling in murine and human tumor cells. Oncogene, doi: 10.1038/onc.2013.75, 2013.
[DLL+13] Dehof, A.K., Loew, S., Lenhof, H.-P., & Hildebrandt, A.: NightShift: NMR Shift Inference by General Hybrid Model Training - a Framework for NMR Chemical Shift Prediction. BMC Bioinformatics, 14(1):98, 2013.


[LKL+12] Ludwig, N., Keller, A., Leidinger, P., Harz, C., Backes, C., Lenhof, H.-P. & Meese, E.: Is there a general autoantibody signature for cancer? Eur J Cancer, 48(15):2451-61, 2012.
[SBN+12] Schmitt, J., Backes, C., Nourkami-Tutdibi, N., Leidinger, P., Deutscher, S., Beier, M., Gessler, M., Graf, N., Lenhof, H.-P., Keller, A., and Meese, E.: Treatment-independent miRNA signature in blood of wilms tumor patients. BMC Genomics, 13:379, 2012.
[SHK+12] Schmitt, J., Heisel, S., Keller, A., Leidinger, P., Ludwig, N., Habel, N., Furtwängler, R., Nourkami-Tutdibi, N., Wegert, J., Grundy, P., Gessler, M., Graf, N., Lenhof, H.-P. & Meese, E.: Multicenter study identified molecular blood-born protein signatures for Wilms Tumor. Int J Cancer, 131(3): 673-682, 2012.
[NSM+12] Nickels, S, Sminia, H, Mueller, S, Kools, B, A.K. Dehof, H.-P. Lenhof, and A. Hildebrandt: (2012) ProteinScanAR - An augmented reality web application for high school education in biomolecular life sciences. Proceedings of the 6th International Symposium on Information Visualization in Biomedical Informatics (IVBI 2012).
[LLH+12] Laczny, C., Leidinger, P., Haas, J., Ludwig, N., Backes, C., Gerasch, A., Kaufmann, M., Vogel, B., Katus, H.-A., Meder, B., Stahler, C., Meese, E., Lenhof, H.-P., and Keller, A.: miRTrail - a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases. BMC Bioinformatics,13:36, 2012.


[BRK+11] Backes, C., Rurainski, A., Klau, G.W., Müller, O., Stöckel, D., Gerasch, A., Küntzer, J., Maisel, D., Ludwig, N., Hein, M., Keller, A., Burtscher, H., Kaufmann, M., Meese, E., and Lenhof, H.-P.: An integer linear programming approach for finding deregulated subgraphs in regulatory networks. Nucleic Acids Res., 40(6):e43, 2011.
[SKN+11] Schmitt, J., Keller, A., Nourkami-Tutdibi, N., Heisel, S., Habel, N., Leidinger, P., Ludwig, N., Gessler, M., Graf, N., Berthold, F., Lenhof, H.-P., and Meese, E.: Autoantibody signature differentiates wilms tumor patients from neuroblastoma patients. PLoS ONE 6(12): e28951, 2011.
[DLH11] Dehof, A.K., Lenhof, H.-P., and Hildebrandt, A.: Predicting Protein NMR Chemical Shifts in the Presence of Ligands and Ions using Force Field-based Features. Proceedings of the German Conference on Bioinformatics (GCB), 2011.
[KLB+11] Keller, A., Leidinger, P., Bauer, A., Elsharawy, A., Haas, A., Backes, C., Wendschlag, A., Giese, N., Tjaden, C., Ott, K., Werner, J., Hackert, T., Ruprecht, K., Huwer, H., Huebers, J., Jacobs, G., Rosenstiel, P., Dommisch, H., Schaefer, A., Müller-Quernheim, J., Wullich, B., Keck, B., Graf, N., Reichrath, J., Vogel, B., Nebel, A., Jager, SU, Staehler, P., Amarantos, I., Biosquerin, V., Staehler, C., Beier, M., Scheffler, M., Büchler, MW., Wischhusen, J., Haeusler, SF, Dietl, J., Hofmann, S., Lenhof, H.-P., Schreiber, S., Katus, HA., Rottbauer, W., Meder, B., Hoheisel, JD., Franke, A. & Meese, E.: Toward the blood-borne miRNome of human diseases. Nat Methods, 8: 841-43, 2011.
[BLL+11] Backes, C., Ludwig, N., Leidinger, P., Harz, C., Hoffmann, J., Keller, A., Meese, E. & Lenhof, H.-P.: Immunogenicity of autoantigens. BMC Genomics, 12:340, 2011.
[SKB+11] Schuler, M., Keller, A., Backes, C., Phillipar, K., Lenhof, H.-P. & Bauer, P.: Transcriptome analysis by Gene Trail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana. BMC Plant Biology, 11:87, 2011.
[KML+11] Küntzer, J., Maisel, D., Lenhof, H.-P., Klostermann, S. & Burtscher H.: The Roche Cancer Genome Database 2.0. BMC Med Genomics, 4:43, 2011.
[KLG+11] Keller, A., Leidinger, P., Gislefoss, R., Haugen, A., Langseth, H., Staehler, P., Lenhof, H.-P. & Meese, E.: Stable serum miRNA profiles as potential tool for non-invasive lung cancer diagnosis. RNA Biol., 8(3): 506-16, 2011.
[LKB+11] Leidinger, P., Keller, A., Borries, A. Huwer, H., Rohling, M. Huebers, J., Lenhof, H.-P. & Meese, E.: Specific peripheral miRNA profiles for distinguishing lung cancer from COPD. Lung Cancer, 74(1): 41-7, 2011.
[DRB+11] Dehof, A.K., Rurainski, A., Bui, Q.B.A., Böcker, S., Lenhof, H.-P. & Hildebrandt, A.: Automated Bond Order Assignment as an Optimization Problem. Bioinformatics, 27(13), 2011.


[HDR+10] Hildebrandt, A., Dehof, A.K., Rurainski, A., Bertsch, A., Schumann, M., Toussaint, N.C., Moll, A., Stöckel, D., Nickels, S., Müller, S.C., Lenhof, H.-P. & Kohlbacher, O.: BALL - Biochemical Algorithms Library 1.3. BMC Bioinformatics, 11:531, 2010.
[MDG+10] Marsalek, L., Georgiev, I., Dehof, A.K., Lenhof, H.-P., Slusallek, P., and Hildebrandt, A.: Real-time Ray Tracing of Complex Molecular Scenes. Proceedings of the IVbm 10 - Information Visualization in Biomedical Informatics, 2010.
[MTH+10] Melchior, K., Tholey, A., Heisel, S., Keller, A., Lenhof, H.-P., Meese, E. & Huber C.G.: Protein-versus peptide fractionation in the first dimension of two-dimensional high-performance liquid chromatography-matrix-assisted laser desorption/ionization tandem mass spectrometry for qualitative proteome analysis of tissue samples. J Chromatogr A., 1217(40): 6159-68, 2010.
[LKB+10] Leidinger, P., Keller, A., Borries, A., Reichrath, J., Rass, K., Jager, S.U., Lenhof, H.-P. & Meese, E.. (2010). High-throughput miRNA profiling of human melanoma blood samples. BMC Cancer 2010, 10:262.
[FLK+10] Fischer, U., Leidinger, P., Keller, A., Folarin, A., Ketter, R., Graf, N., Lenhof, H.-P. & Meese, E. (2010). Amplicons on chromosome 12q13-21 in glioblastoma recurrences. Int J Cancer, 2010, 126(11):2594-602.
[PGDN+10] M. Phillips, I. Georgiev, A.K. Dehof, L. Marsalek, H.-P. Lenhof, A. Hildebrandt, and P. Slusallek: (2010) Measuring Properties of Molecular Surfaces Using Ray Casting. HiCOMB 2010, Proceedings of 9th International Workshop on High Performance Computational Biology
[LKH+10] Ludwig, N., Keller, A., Heisel, S., Leidinger, P., Rheinheimer, S., Andres, C., Stephan, B., Steudel, W.-I., Donauer, E., Graf, N., Burgeth, B., Weickert, J., Lenhof, H.-P., & Meese, E. (2010). Novel immunogenic antigens increase classification accuracy in meningioma to 93.84%. Int J Cancer, 9999(999A)



Center for Bioinformatics
Saarland University
Building E 2.1
Room 416
P.O. Box 15 11 50
66041 Saarbrücken