Prof. Dr. Hans-Peter Lenhof
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This is the personal page of Hans-Peter Lenhof
My Publications
2018
[KFL+18] Keller, A., Fehlmann, T., Ludwig, N., Kahraman, M., Laufer, T., Backes, C., Vogelmeier, C., Diener, C., Biertz, F., Herr, C., Jörres, R.A., Lenhof, H.-P., Meese, E., Bals, R., COSYCONET Study Group.Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development. Genomics, Proteomics & Bioinformatics 16 (3), 162-171, 2018. DOI: 10.1016/j.gpb.2018.06.001.
[KSK+18] Kehl, T., Schneider, L., Kattler, K., Stöckel, D., Wegert, J., Gerstner, N., Ludwig, N., Distler, U., Schick, M., Keller, U., Tenzer, S., Gessler, M., Walter, J., Keller, A., Graf, N., Meese, E., Lenhof, H.-P. REGGAE: a novel approach for the identification of key transcriptional regulators. Bioinformatics. Bioinformatics 34 (20), 3503-3510, 2018. DOI: 10.1093/bioinformatics/bty372.
2017
[FBA+17] Fehlmann, T., Backes, C., Alles, J., Fischer, U., Hart, M., Kern, F., Langseth, H., Rounge, T., Umu, S.U., Kahraman, M., Laufer, T., Haas, J., Staehler, C., Ludwig, N., Hübenthal, M., Meder, B., Franke, A., Lenhof, H.-P., Meese, E., Keller, A. A high-resolution map of the human small non-coding transcriptome. Bioinformatics 34 (10), 1621-1628, 2017. DOI: 10.1093/bioinformatics/btx814.
[KBK+17] Kehl, T., Backes, C., Kern, F., Fehlmann, T., Ludwig, N., Meese, E., Lenhof, H.-P., Keller, A. About miRNAs, miRNA seeds, target genes and target pathways. Oncotarget 8 (63), 107167, 2017. DOI: 10.18632/oncotarget.22363.
[BFK+17] Backes, C., Fehlmann, T., Kern, F., Kehl, T., Lenhof, H.-P., Meese, E., Keller, A. miRCarta: a central repository for collecting miRNA candidates. Nucleic Acids Research 46 (D1), D160-D167, 2017. DOI: 10.1093/nar/gkx851.
[KSS+17] Kehl, T., Schneider, L., Schmidt, F., Stöckel, D., Gerstne,r N., Backes, C., Meese, E., Keller, A., Schulz, M.H., Lenhof, H.-P. RegulatorTrail: a web service for the identification of key transcriptional regulators. Nucleic Acids Research 45 (W1), W146-W153, 2017. DOI: 10.1093/nar/gkx350.
[BKS+17] Backes C., Kehl T., Stöckel D., Fehlmann T., Schneider L., Meese E., Lenhof H.-P., Keller A. miRPathDB: a new dictionary on microRNAs and target pathways. Nucleic Acids Res. 2017 Jan 4;45(D1):D90-D96. doi: 10.1093/nar/gkw926
2016
[BLL+16] Backes, C., Ludwig, N., Leidinger, P., Huwer, H., Tenzer, S., Fehlmann, T., Franke, A., Meese, E., Lenhof, H.-P., Keller, A. Paired proteomics, transcriptomics and miRNomics in non-small cell lung cancers: known and novel signaling cascades. Oncotarget 7 (44), 71514, 2017. DOI: 10.18632/oncotarget.11723.
[SSK+16] Schneider, L., Stöckel, D., Kehl, T., Gerasch, A., Ludwig, N., Leidinger, P., Huwer, H., Tenzer, S., Kohlbacher, O., Hildebrandt, A., Kaufmann, M., Gessler, M., Keller, A., Meese, E., Graf, N., and Lenhof, H.-P.: DrugTargetInspector: An assistance tool for patient treatment stratification.
Int J Cancer. 2016 Apr 1;138(7):1765-76. doi: 10.1002/ijc.29897.
[LWB+16] Ludwig, N., Werner, T.V., Backes, C., Trampert, P., Gessler, M., Keller, A., Lenhof, H.-P., Graf, N., and Meese E.:
Combining miRNA and mRNA Expression Profiles in Wilms Tumor Subtypes.
Int J Mol Sci. 2016 Mar 30;17(4). pii: E475. doi: 10.3390/ijms17040475.
[TLB+16] Tenzer, S., Leidinger, P., Backes, C., Huwer, H., Hildebrandt, A., Lenhof, H.-P., Wesse, T., Franke, A., Meese, E., and Keller, A.:
Integrated quantitative proteomic and transcriptomic analysis of lung tumor and control tissue: a lung cancer showcase.
Oncotarget. 2016 Feb 22. doi: 10.18632/oncotarget.7562. [Epub ahead of print]
[MBM+16] Marx, A., Backes, C., Meese, E., Lenhof, H.-P., and Keller, A.:
EDISON-WMW: Exact Dynamic Programing Solution of the Wilcoxon-Mann-Whitney Test.
Genomics Proteomics Bioinformatics. 2016 Feb;14(1):55-61. doi: 10.1016/j.gpb.2015.11.004. [Epub 2016 Jan 29]
[SKT+16] Stöckel, D., Kehl, T., Trampert, P., Schneider, L., Backes, C., Ludwig, N., Gerasch, A., Kaufmann, M., Gessler, M., Graf, N., Meese, E., Keller, A., Lenhof, H.P.,: Multi-omics Enrichment Analysis using the GeneTrail2 Web Service. Bioinformatics 2016; doi: 10.1093/bioinformatics/btv770
2015
[SST+15]
Stöckel, D., Schmidt, F., Trampert, P., and Lenhof, H.-P.: CausalTrail: Testing hypothesis using causal Bayesian networks. F1000Research 2015, 4(ISCB Comm J):1520, doi: 10.12688/f1000research.7647.1
[MBK+15] Mueller, S.C., Backes, C. , Kalinina, O. V., Meder, B., Stöckel, D., Lenhof, H.-P., Meese, E. and Keller, A. BALL-SNP: combining genetic and structural information to identify candidate non-synonymous single nucleotide polymorphisms. Genome Medicine. 2015, 7:65, DOI:10.1186/s13073-015-0190-y
[LKM+15]
Leidinger, P., Keller, A., Milchram, L., Harz, C., Hart, M., Werth, A., Lenhof, H.-P., Weinhäusel, A., Keck, B., Wullich, B., Ludwig, N., and Meese, E.: Combination of Autoantibody Signature with PSA Level Enables a Highly Accurate Blood-Based Differentiation of Prostate Cancer Patients from Patients with Benign Prostatic Hyperplasia.
PLoS One. 2015 Jun 3;10(6):e0128235. doi: 10.1371/journal.pone.0128235. eCollection 2015.
[LNB+15] Ludwig, N., Nourkami-Tutdibi, N., Backes, C., Lenhof, H.-P., Graf, N., Keller, A., and Meese, E. Circulating serum miRNAs as potential biomarkers for nephroblastoma. Pediatr Blood Cancer, Wiley Periodicals, Inc.; 2015 March 18 doi: 10.1002/pbc.25481. [Epub ahead of print]
[GKN+15] Gerasch, A., Küntzer, J., Niermann, P., Stöckel, S., Kaufmann, M., Kohlbacher, O., Lenhof, H.-P., Network-based interactive navigation and analysis of large biological datasets, it - Information Technology. Volume 57, Issue 1, Pages 37–48, ISSN (Online) 2196-7032, ISSN (Print) 1611-2776, DOI: 10.1515/itit-2014-1076, January 2015
[HWL+15]
Hellmuth, M., Wieseke, N., Lechner, M., Lenhof, H.-P., Middendorf, M., and Stadler, P.F.: Phylogenomics with Paralogs. Proceedings of the National Academy of Sciences (PNAS), 112/7: 2058-63, 2015.
[SL15]
Stöckel, D. and Lenhof, H.-P.: Detecting Dysregulated Processes and Pathways. Chapter 14, 309-324 in Nucleic Acids as Molecular Diagnostics. Edited by Andreas Keller and Eckart Meese (First Edition, Wiley-VCH Verlag, ISBN: 978-3-527-33556-5), 2015.
2014
[AKH+14] Hildebrandt, A. K., Stöckel D., Fischer, N. M., de la Garza, L., Krüger, J., Nickels, S., Röttig, M., Schärfe, C., Schumann, M., Thiel, P., Lenhof, H.-P., Kohlbacher, O., and Andreas Hildebrandt, ballaxy: web services for structural bioinformatics, Bioinformatics 2014, doi: 10.1093/bioinformatics/btu574
[BRS+14] Backes, C., Rühle, F., Stoll, M., Haas, J., Frese, K., Franke, A., Lieb, W., Wichmann, H.-E., Weis, T., Kloos, W., Lenhof, H.-P., Meese, E., Katus, H., Meder, B., and Keller, A.:
Systematic permutation testing in GWAS pathway analyses: identification of genetic networks in dilated cardiomyopathy and ulcerative colitis.
BMC Genomics. Jul 22;15(1):622, 2014.
[HDL+14] Hildebrandt, A.K., Dietzen, M., Lengauer, T., Lenhof, H.-P., Althaus, E., and Hildebrandt, A.
Efficient computation of root mean square deviations under rigid transformations.
J Comput Chem. 35(10):765–771, 2014
[GFK+14]
Gerasch, A., Faber, D., Küntzer, J., Niermann, J., Kohlbacher, O., Lenhof, H.-P., and Kaufmann, M.: BiNA: A Visual Analytics Tool for Biological Network Data. PLOS ONE 10.1371, 2014.
2013
[NSM+13] Nickels, S., Stöckel, D., Mueller, S.C., Lenhof, H.-P., Hildebrandt, A., and Dehof, A.K.: PresentaBALL – a Powerful Package for Presentations and Lessons in Structural Biology. BioVis - 3rd IEEE Symposium on Biological Data Visualization, 2013.
