A well studied problem in the area of Computational Molecular Biology is the so-called Protein-Protein Docking problem (PPD). Given two proteins A and B that form a protein complex, compute the 3D-structure of the protein complex AB.
Protein docking algorithms can help to build hypotheses about the driving forces and reaction mechanisms of docking processes. Furthermore, they can be used to predict protein-protein interactions and to speed up the lengthy process of experimental structure elucidation of protein complexes by proposing putative complex structures.
The main goal of the project is the development and implementation of algorithms for predicting the 3D-structure and the stability of protein complexes.
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