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Kerstin Lenhof


My name is Kerstin Lenhof, and I am a PhD candidate from Saarland University/Saarbrücken Graduate School of Computer Science working as a researcher at the chair of Prof. Dr. Hans-Peter Lenhof (incidental name similarity).
Amongst others, we develop bioinformatics software and databases for analysing human diseases, e.g., cancer, at this chair.
I am particularly interested in the development of novel algorithms and approaches for drug sensitivity prediction and biomarker discovery
in cancer.

  • M. Sc. in Computational Molecular Biology, Saarland University September 2018
  • B. Sc. in Computational Molecular Biology, Saarland University March 2016
  • Research: 
  • Personalized medicine
  • Machine learning in bioinformatics
  • Cancer research
  • Multi-omics integrative analyses
  • Teaching: 

    Teaching Assistant:

  • Project Seminar: Machine Learning: SS18
  • Bioinformatics I: WS19/20, WS22/23
  • Bioinformatics II: SS19, SS22
  • Seminar 'Machine Learning Applications in Bioinformatics': SS21, WS21/22, SS22
  • Seminar 'Computational Biomarker Discovery': SS20, WS20/21
  • Seminar 'Bioinformatic Approaches for Personalized Cancer Treatment': SS19, WS19/20
  • Thesis supervisor:

  • completed: 3 bachelor's theses, 5 master's theses
  • ongoing: 4 bachelor's theses, 2 master's theses


  • Bioinformatics I: WS15/16
  • Bioinformatics II: SS16
  • Mathematics for Computer Scientists I: WS14/15
  • Mathematics for Computer Scientists II: SS15
  • Preparatory Course in Mathematics for Computer Scientists: WS14/15, WS15/16
  • My Publications


    [LEG+22] Lenhof, K., Eckhart, L., Gerstner, N., Kehl, T., Lenhof, H.-P. Simultaneous regression and classification for drug sensitivity prediction using an advanced random forest method. Scientific Reports, 2022. DOI: 10.1038/s41598-022-17609-x.


    [GKL+21] Gerstner, N., Kehl, T., Lenhof, K., Eckhart, L., Schneider, L., Stöckel, D., Backes, C., Meese, E., Keller, A., Lenhof, H.-P. GeneTrail: A Framework for the Analysis of High-Throughput Profiles. Frontiers in Molecular Biosciences, 2021. DOI: 10.3389/fmolb.2021.716544.
    [LGK+21] Lenhof, K., Gerstner, N., Kehl, T., Eckhart, L., Schneider, L., Lenhof, H.-P. MERIDA: a novel Boolean logic-based integer linear program for personalized cancer therapy. Bioinformatics, btab 546, 2021. DOI: 10.1093/bioinformatics/btab546.


    [DHK+20] Diener, C., Hart, M., Kehl, T., Rheinheimer, S., Ludwig, N.,Krammes, L., Pawusch, S., Lenhof, K., Tänzer, T., Schub, D., Sester, M., Walch-Rückheim,B., Keller, A., Lenhof, H.-P., Meese, E. Quantitative and time-resolved miRNA pattern of early human T cell activation. Nucleic Acids Research, 2020. DOI: 10.1093/nar/gkaa788.
    [GKL+20] Gerstner, N., Kehl, T., Lenhof, K., Müller, A., Mayer, C., Eckhart, L., Grammes, N.L., Diener, C., Hart, M., Hahn, O., Walter, J., Wyss-Coray, T., Meese, E., Keller, A., Lenhof, H.-P. GeneTrail 3: advanced high-throughput enrichment analysis. Nucleic Acids Research, 2020. DOI:10.1093/nar/gkaa306.


    [SKT+19] Schneider, L., Kehl, T., Thedinga, K., Grammes, N. L., Backes, C., Mohr, C., Schubert, B., Lenhof, K., Gerstner, N., Hartkopf. A. D., Wallwiener, M., Kohlbacher, O., Keller, A., Meese, E., Graf, N., Lenhof, H.-P. ClinOmicsTrail bc: a visual analytics tool for breast cancer treatment stratification, Bioinformatics, btz302, 2019. DOI: 10.1093/bioinformatics/btz302.


    Center for Bioinformatics
    Saarland Informatics Campus
    Saarland University
    Building E 2.1
    Room 402
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