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Daniel Stöckel, M. Sc.

Employment: 
Researcher
Personal: 

My name is Daniel Stöckel. I am a PhD student on the chair of Professor Hans-Peter Lenhof. On this site you can find information on my research interests, publications and teaching conducted by me.

Education: 

I obtained my Abitur in 2005. In 2008 i finished my Bachelor of Science in Bioinformatics at the Saarland University and was admitted to the Graduate School Program. I obtained my Master of Science in Bioinformatics in early 2010.

Research: 

My research interests lie in the field of structural bioinformatics, especially molecular docking. Here I am working on the development of new scoring functions with a focus on data driven and hybrid approaches. I also collaborate with other members of my group in the field of network and transcription analysis.

Teaching: 

Tutoring

  • Programming I (WS 06/07)
  • Programming II (SS 07)
  • Softwarepraktikum (SS 07)
  • Mathematics for Computer Scientists - Tutorial for Bioinformaticians (WS 07/08)
  • Programming II (SS 08)
  • Bioinformatics II (SS 09)

Teaching Assistant

  • Bioinformatics I (WS 10/11)
  • Bioinformatics II (SS 11)
  • Bioinformatics I (WS 11/12)

My Publications

2018

[KSK+18] Kehl T, Schneider L, Kattler K, Stöckel D, Wegert J, Gerstner N, Ludwig N, Distler U, Tenzer S, Gessler M, Walter J, Keller A, Graf N, Meese E, Lenhof HP. The role of TCF3 as potential master regulator in blastemal Wilms tumors. International Journal of Cancer. (in production).
[KSK+18] Kehl T, Schneider L, Kattler K, Stöckel D, Wegert J, Gerstner N, Ludwig N, Distler U, Schick M, Keller U, Tenzer S, Gessler M, Walter J, Keller A, Graf N, Meese E, Lenhof HP. REGGAE: a novel approach for the identification of key transcriptional regulators. Bioinformatics. 2018 May 7. doi: 10.1093/bioinformatics/bty372.

2017

[KSS+17] Kehl T, Schneider L, Schmidt F, Stöckel D, Gerstner N, Backes C, Meese E, Keller A, Schulz MH, Lenhof HP. RegulatorTrail: a web service for the identification of key transcriptional regulators. Nucleic Acids Res. 2017 Jul 3;45(W1):W146-W153. doi: 10.1093/nar/gkx350.
[BKS+17] Backes C., Kehl T., Stöckel D., Fehlmann T., Schneider L., Meese E., Lenhof H.-P., Keller A. miRPathDB: a new dictionary on microRNAs and target pathways. Nucleic Acids Res. 2017 Jan 4;45(D1):D90-D96. doi: 10.1093/nar/gkw926

2016

[SSK+16] Schneider, L., Stöckel, D., Kehl, T., Gerasch, A., Ludwig, N., Leidinger, P., Huwer, H., Tenzer, S., Kohlbacher, O., Hildebrandt, A., Kaufmann, M., Gessler, M., Keller, A., Meese, E., Graf, N., and Lenhof, H.-P.: DrugTargetInspector: An assistance tool for patient treatment stratification. Int J Cancer. 2016 Apr 1;138(7):1765-76. doi: 10.1002/ijc.29897.
[SKT+16] Stöckel, D., Kehl, T., Trampert, P., Schneider, L., Backes, C., Ludwig, N., Gerasch, A., Kaufmann, M., Gessler, M., Graf, N., Meese, E., Keller, A., Lenhof, H.P.,: Multi-omics Enrichment Analysis using the GeneTrail2 Web Service. Bioinformatics 2016; doi: 10.1093/bioinformatics/btv770

2015

[SST+15] Stöckel, D., Schmidt, F., Trampert, P., and Lenhof, H.-P.: CausalTrail: Testing hypothesis using causal Bayesian networks. F1000Research 2015, 4(ISCB Comm J):1520, doi: 10.12688/f1000research.7647.1
[MBK+15] Mueller, S.C., Backes, C. , Kalinina, O. V., Meder, B., Stöckel, D., Lenhof, H.-P., Meese, E. and Keller, A. BALL-SNP: combining genetic and structural information to identify candidate non-synonymous single nucleotide polymorphisms. Genome Medicine. 2015, 7:65, DOI:10.1186/s13073-015-0190-y
[GKN+15] Gerasch, A., Küntzer, J., Niermann, P., Stöckel, S., Kaufmann, M., Kohlbacher, O., Lenhof, H.-P., Network-based interactive navigation and analysis of large biological datasets, it - Information Technology. Volume 57, Issue 1, Pages 37–48, ISSN (Online) 2196-7032, ISSN (Print) 1611-2776, DOI: 10.1515/itit-2014-1076, January 2015
[SL15] Stöckel, D. and Lenhof, H.-P.: Detecting Dysregulated Processes and Pathways. Chapter 14, 309-324 in Nucleic Acids as Molecular Diagnostics. Edited by Andreas Keller and Eckart Meese (First Edition, Wiley-VCH Verlag, ISBN: 978-3-527-33556-5), 2015.

2014

[AKH+14] Hildebrandt, A. K., Stöckel D., Fischer, N. M., de la Garza, L., Krüger, J., Nickels, S., Röttig, M., Schärfe, C., Schumann, M., Thiel, P., Lenhof, H.-P., Kohlbacher, O., and Andreas Hildebrandt, ballaxy: web services for structural bioinformatics, Bioinformatics 2014, doi: 10.1093/bioinformatics/btu574

2013

[NSM+13] Nickels, S., Stöckel, D., Mueller, S.C., Lenhof, H.-P., Hildebrandt, A., and Dehof, A.K.: PresentaBALL – a Powerful Package for Presentations and Lessons in Structural Biology. BioVis - 3rd IEEE Symposium on Biological Data Visualization, 2013.
[SMK+13] Stöckel, D., Müller, O., Kehl, T., Gerasch, A., Backes, C., Rurainski, A., Keller, A., Kaufmann, M., and Lenhof, H.-P.: NetworkTrail - A web service for identifying and visualizing deregulated subnetworks. Bioinformatics 29 (13):1702-03, 2013.
[LBH+13] Li, D., Beisswenger, C., Herr, C., Hellberg, J., Han, G., Zakharkina, T., Voss, M., Wiewrodt, R., Bohle, R.M., Menger, M.D., Schmid, R.M., Stöckel, D., Lenhof, H.-P., and Bals, R.: Myeloid cell RelA/p65 promotes lung cancer proliferation through Wnt/β-catenin signaling in murine and human tumor cells. Oncogene, doi: 10.1038/onc.2013.75, 2013.

2012

[BDZ+12] Bogojeska, J., Stöckel, D., Zazzi, Z., Rolf, K., Francesca, I., Michal, R-Z., Lengauer, T. History-alignment models for bias-aware prediction of virological response to HIV combination therapy. AISTATS 2012.

2011

[BRK+11] Backes, C., Rurainski, A., Klau, G.W., Müller, O., Stöckel, D., Gerasch, A., Küntzer, J., Maisel, D., Ludwig, N., Hein, M., Keller, A., Burtscher, H., Kaufmann, M., Meese, E., and Lenhof, H.-P.: An integer linear programming approach for finding deregulated subgraphs in regulatory networks. Nucleic Acids Res., 40(6):e43, 2011.

2010

[HDR+10] Hildebrandt, A., Dehof, A.K., Rurainski, A., Bertsch, A., Schumann, M., Toussaint, N.C., Moll, A., Stöckel, D., Nickels, S., Müller, S.C., Lenhof, H.-P. & Kohlbacher, O.: BALL - Biochemical Algorithms Library 1.3. BMC Bioinformatics, 11:531, 2010.

Contact

Address:
Center for Bioinformatics
Saarland University
Building E 2.1
Room 402
P.O. Box 15 11 50
66041 Saarbrücken Germany
Email:
dstoeckel [AT] bioinf.uni-sb.de
Fax:
+49-681-302-64719
Phone:
+49-681-302-70896