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Prof. Dr. Hans-Peter Lenhof

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This is the personal page of Hans-Peter Lenhof

My Publications

2011

[KLB+11] Keller, A., Leidinger, P., Bauer, A., Elsharawy, A., Haas, A., Backes, C., Wendschlag, A., Giese, N., Tjaden, C., Ott, K., Werner, J., Hackert, T., Ruprecht, K., Huwer, H., Huebers, J., Jacobs, G., Rosenstiel, P., Dommisch, H., Schaefer, A., Müller-Quernheim, J., Wullich, B., Keck, B., Graf, N., Reichrath, J., Vogel, B., Nebel, A., Jager, SU, Staehler, P., Amarantos, I., Biosquerin, V., Staehler, C., Beier, M., Scheffler, M., Büchler, MW., Wischhusen, J., Haeusler, SF, Dietl, J., Hofmann, S., Lenhof, H.-P., Schreiber, S., Katus, HA., Rottbauer, W., Meder, B., Hoheisel, JD., Franke, A. & Meese, E.: Toward the blood-borne miRNome of human diseases. Nat Methods, 8: 841-43, 2011.
[BLL+11] Backes, C., Ludwig, N., Leidinger, P., Harz, C., Hoffmann, J., Keller, A., Meese, E. & Lenhof, H.-P.: Immunogenicity of autoantigens. BMC Genomics, 12:340, 2011.
[SKB+11] Schuler, M., Keller, A., Backes, C., Phillipar, K., Lenhof, H.-P. & Bauer, P.: Transcriptome analysis by Gene Trail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana. BMC Plant Biology, 11:87, 2011.
[KML+11] Küntzer, J., Maisel, D., Lenhof, H.-P., Klostermann, S. & Burtscher H.: The Roche Cancer Genome Database 2.0. BMC Med Genomics, 4:43, 2011.
[KLG+11] Keller, A., Leidinger, P., Gislefoss, R., Haugen, A., Langseth, H., Staehler, P., Lenhof, H.-P. & Meese, E.: Stable serum miRNA profiles as potential tool for non-invasive lung cancer diagnosis. RNA Biol., 8(3): 506-16, 2011.
[LKB+11] Leidinger, P., Keller, A., Borries, A. Huwer, H., Rohling, M. Huebers, J., Lenhof, H.-P. & Meese, E.: Specific peripheral miRNA profiles for distinguishing lung cancer from COPD. Lung Cancer, 74(1): 41-7, 2011.
[DRB+11] Dehof, A.K., Rurainski, A., Bui, Q.B.A., Böcker, S., Lenhof, H.-P. & Hildebrandt, A.: Automated Bond Order Assignment as an Optimization Problem. Bioinformatics, 27(13), 2011.

2010

[HDR+10] Hildebrandt, A., Dehof, A.K., Rurainski, A., Bertsch, A., Schumann, M., Toussaint, N.C., Moll, A., Stöckel, D., Nickels, S., Müller, S.C., Lenhof, H.-P. & Kohlbacher, O.: BALL - Biochemical Algorithms Library 1.3. BMC Bioinformatics, 11:531, 2010.
[MDG+10] Marsalek, L., Georgiev, I., Dehof, A.K., Lenhof, H.-P., Slusallek, P., and Hildebrandt, A.: Real-time Ray Tracing of Complex Molecular Scenes. Proceedings of the IVbm 10 - Information Visualization in Biomedical Informatics, 2010.
[MTH+10] Melchior, K., Tholey, A., Heisel, S., Keller, A., Lenhof, H.-P., Meese, E. & Huber C.G.: Protein-versus peptide fractionation in the first dimension of two-dimensional high-performance liquid chromatography-matrix-assisted laser desorption/ionization tandem mass spectrometry for qualitative proteome analysis of tissue samples. J Chromatogr A., 1217(40): 6159-68, 2010.
[LKB+10] Leidinger, P., Keller, A., Borries, A., Reichrath, J., Rass, K., Jager, S.U., Lenhof, H.-P. & Meese, E.. (2010). High-throughput miRNA profiling of human melanoma blood samples. BMC Cancer 2010, 10:262.
[FLK+10] Fischer, U., Leidinger, P., Keller, A., Folarin, A., Ketter, R., Graf, N., Lenhof, H.-P. & Meese, E. (2010). Amplicons on chromosome 12q13-21 in glioblastoma recurrences. Int J Cancer, 2010, 126(11):2594-602.
[PGDN+10] M. Phillips, I. Georgiev, A.K. Dehof, L. Marsalek, H.-P. Lenhof, A. Hildebrandt, and P. Slusallek: (2010) Measuring Properties of Molecular Surfaces Using Ray Casting. HiCOMB 2010, Proceedings of 9th International Workshop on High Performance Computational Biology
[LKH+10] Ludwig, N., Keller, A., Heisel, S., Leidinger, P., Rheinheimer, S., Andres, C., Stephan, B., Steudel, W.-I., Donauer, E., Graf, N., Burgeth, B., Weickert, J., Lenhof, H.-P., & Meese, E. (2010). Novel immunogenic antigens increase classification accuracy in meningioma to 93.84%. Int J Cancer, 9999(999A)
[KEL+10] Küntzer, J., Eggle, D., Lenhof, H.-P., Burtscher, H. & Klostermann, S.: The Roche Cancer Genome Database (RCGDB). Hum Mutat. 3(4), 407-13, 2010.
[BML+10] Backes, C., Meese, E., Lenhof, H.-P., & Keller, A. (2010). A dictionary on microRNAs and their putative target pathways. Nucleic Acids Res. 2010 Mar 18. [Epub ahead of print].
[LKH+10] Leidinger, P., Keller, A., Heisel, S. Ludwig, N., Rheinheimer, S., Klein, V., Andres, C., Staratschek-Jox, A., Wolf, J., Stoelben, E., Stephan, B., Stehle, I., Hamacher, J., Huwer, H., Lenhof, H.-P., & Meese, E. (2010). Identification of lung cancer with high sensitivity and specificity by blood testing. Respiratory Research 2010, 11:18.
[FRL+10] Jan Fuhrmann, Alexander Rurainski, Hans-Peter Lenhof, and Dirk Neumann. A new Lamarckian genetic algorithm for flexible ligand-receptor docking. J Comput Chem., 31(9), 1911-18, 2010.

2009

[DGMS+09] A. K. Dehof, I. Georgiev, L. Marsalek, D. Stöckel, S. Nickels, H.-P. Lenhof, P. Slusallek and A. Hildebrandt (2009): Visual Computing in Computer Aided Drug Design. Visual Computing Research Conference, Saarbrücken, Germany, 8-10 December 2009
[LKH+09] Ludwig, N., Keller A., Heisel, S., Leidinger, P., Klein, V., Rheinheimer, S., Andres, C.U., Stephan, B., Steudel, W-I., Graf, N.M., Burgeth, B., Weickert, J., Lenhof, H.-P., & Meese, E. (2009). Improving Seroreactivity-Based Detection of Glioma. Neoplasia, 11 (12): 1383-89.
[KLL+09] Keller, A., Leidinger, P., Lange, J., Borries, A., Schroers, H., Scheffler, M., Lenhof, H.-P., Ruprecht, K. & Meese, E. (2009). Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls. PLoS One, 4(10):e7440.
[MTH+09] Melchior, K., Tholey, A., Heisel, S., Keller, A., Lenhof, H.-P., Meese, E. & Huber C.G. (2009). Proteomic study of human glioblastoma multiforme tissue employing complementary two-dimensional liquid chromatography-mass spectrometry-based approaches. J. Proteome Res., 8(19):4604-14.
[KLB+09] Keller, A., Leidinger, P., Borries, A., Wendschlag, A., Wucherpfennig, F., Scheffler, M., Huwer, H., Lenhof, H.-P., & Meese, E. (2009). miRNAs in lung cancer - Studying complex fingerprints in patient's blood cells by microrarray experiments. BMC Cancer, 9:353.
[DRL+09] Dehof, A. K., Rurainski, A., Lenhof, H.-P., and Hildebrandt, A.: Automated Bond Order Assignment as an Optimization Problem. Proceedings of the German Conference on Bioinformatics (GCB), Lecture Notes in Informatics, 2009.
[KBG+09] Keller, A., Backes, C., Gerasch, A., Kaufmann, M., Kohlbacher, O., Meese, E., & Lenhof, H.-P. (2009). A novel algorithm for detecting differentially regulated paths based on Gene Set Enrichment Analysis. Bioinformatics, 25:2787-94.

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Contact

Address:
Center for Bioinformatics
Saarland University
Building E 2.1
Room 416
P.O. Box 15 11 50
66041 Saarbrücken
Germany
Email:
len@bioinf.uni-sb.de
Fax:
+49-681-302-64719
Phone:
+49-681-302-64701